Avapro (Irbesartan) Information

The active ingredient in Avapro is Irbesartan, available in two strengths: 150 mg and 300 mg per tablet. Other inactive ingredients may include:

• Lactose monohydrate: Approximately 100 mg – a filler and stabilizer used in tablet formation.
• Microcrystalline cellulose: Approximately 50 mg – a stabilizer and filler that helps maintain tablet integrity.
• Croscarmellose sodium: Approximately 10 mg – an excipient that aids in the tablet’s dissolution and absorption.
• Silicon dioxide: Approximately 5 mg – an anti-caking agent that prevents the ingredients from sticking together.
• Magnesium stearate: Approximately 2 mg – a lubricant that helps in the manufacturing process, ensuring smooth tablet production.

Common side effects include:

• Dizziness
• Fatigue
• Upset stomach
• Muscle pain

Serious side effects that require immediate medical attention:

• Severe dizziness or fainting
• High potassium levels (muscle weakness, irregular heartbeat)
• Decreased kidney function (change in urine output)
• Swelling of the face, lips, or throat (angioedema)

Avapro is usually taken once daily, with or without food. It is important to take it at the same time each day for best results. Patients should swallow the tablet whole with a glass of water.

Important considerations:

• Do not stop taking Avapro without consulting a doctor.
• Stay hydrated but avoid excessive potassium intake.
• Avoid alcohol, as it may increase dizziness.

Avapro can interact with several medications, so it is essential to consult a doctor before combining it with other drugs.

Common interactions:

• Diuretics (water pills): May increase the risk of low blood pressure.
• NSAIDs (e.g., ibuprofen, naproxen): May reduce the effectiveness of Avapro.
• Potassium supplements or potassium-sparing diuretics: Can lead to high potassium levels.
• Diabetes medications or insulin: May enhance blood sugar-lowering effects.

Avapro starts lowering blood pressure within a few hours, but the full effect may take 2 to 4 weeks. Some patients may feel improvements in symptoms like dizziness or shortness of breath within a few days, but consistent use is needed for optimal benefits.

For kidney protection, noticeable benefits may take several months as the medication gradually reduces the progression of kidney damage.

If you experience severe side effects such as difficulty breathing, swelling of the face, lips, or throat, or an allergic reaction, seek emergency medical attention immediately.

If you notice persistent dizziness, fainting, or a significant decrease in urine output, contact your doctor right away. These symptoms may indicate a serious reaction requiring medical intervention.

For milder side effects like fatigue or muscle pain, discuss with your doctor whether dosage adjustments or alternative medications are needed.